Research Topics

① Isolation and characterization of novel enzymes from microorganisms
② Enzymological and microbial production of industrially useful compounds and D-amino acids
③ Analysis and function of D-amino acids in foods

Key Words

D-Amino Acid, Novel Enzyme, Stereospecific Synthesis, Biocatalyst, Screening of Novel Microorganisms, Fermentative Food, Thermostable Enzymes

Applications

Production of Food Additive, Functional Food, Medicine, Agricultural Chemicals, and Biopolymer; Food Process; Biomass; Biosensor

Research Topics

① Genomics-guided Discovery of Biosynthetic Genes for Novel Bioactive Molecules
② Biosynthetic Studies for Structurally Unique Microbial Bioactive Molecules
③ Development of a Genetic Platform for Efficient Production of Bioactive Molecules

Key Words

Genome-mining, Natural product, Biosynthesis,
Microbial genetics, Actinobacteria,
microbial production, fermentation

Applications

Pharmaceutical and Agricultural drugs,
Food preservatives, Cosmetics, Biopolymers, Chemicals

Research Topics

① Genetic Analysis of Xenobiotics-Degrading Bacteria
② Exploration of Untapped Microbial Resources
③ Development of Functional Analysis Tools for Environmental Microorganisms

Key Words

Applied and Environmental Microbiology, Biodegradation, Bioconversion, Bioproduction, Genome Editing, Metabolic Engineering

Applications

Bioremediation of Xenobiotics, Bioproduction of Useful Chemicals, Wastewater Treatment

Research Topics

① Construction of Artificial Microbiota
② Metabolic Engineering of Microorganisms
③ Genome Editing of Microorganisms

Key Words

Artificial Microbiota, Metabolic Engineering, Genome Editing, Cell Penetrating Peptide, Peptide Nucleic Acid, Bacteriophage

Applications

Bio-refinery, Production of Useful Compounds, Modification of Microbial Functions, Analysis of Microbial Interactions

Research Topics

① Production of immunostimulating polysaccharides by lactic acid bacteria.
② Cultivation of lactic acid bacteria to a concentration one order of magnitude higher than before.
③ Improving the efficiency of enzymatic saccharification of cellulose.

Key Words

lactic acid bacteria, fed-batch culture, immunostimulating polysaccharide, enzymatic saccharification of cellulose

Applications

Efficient production of lactic acid bacteria and their product such as immunostimulating polysaccharides.

Research Topics

① Analysis of biological regulatory mechanisms of intestinal bacteria
② Functional analysis of membrane vesicles produced by intestinal bacteria
③ Development of purification and quantification methods for bacterial membrane vesicles

Key Words

Intestinal bacteria , Probiotics , Membrane vesicle , Gut immunity

Applications

Intestinal bacteria , Probiotics , Membrane vesicle , Gut immunity

Research Topics

① Disinfection of microorganisms
② Investigation of biofilm formation and development of biofilm removal system
③ Bioremediation of chemical pollutants by environmental bacteria and their activities
④ Outbreak mechanism of stress resistant bacterial and their resistant mechanism
⑤ Bioenergy production and biomass utilization

Key Words

Disinfectant, Sterilization System, Biofilm, Surfactant, Reactive Oxygen Species, Stress Response, Molecular Chaperone, Protein Stability, Bioremediation, Chemical Pollutant, Cytochrome P450 Monooxygenase, Genetics, Endogenous Plasmid, Biodiesel, bioenerg

Applications

Sewage Disposal System, Improvement of Polluted Soil, Development of Disinfectant, Food Processing, Pharmaceutical Manufacturing, Medicals, Enzymatic Industry

Research Topics

① Development of novel antimicrobial technology
② Production of useful compounds by microoraganism
③ Environmental impact assessment and bioremediation

Key Words

Antimicrobial compound, Antimicrobial action, Antimicrobial resistance, Biofilm, Biorefinery, Environmental impact assessment, Bioremediation

Applications

Microbial control, Antimicrobial technology

Research Topics

① We study on the absorption, metabolism, nutrigenomics, and chemistry of marine functional compounds such as n-3 polyunsaturated fatty acid or marine organic compounds.
② Our research project also includes attempts to improve protein functionality, food process characteristics and biofunctions, using molecular modification.

Key Words

Fish Oil, n-3 Polyunsaturated Fatty Acid, Fish Protein, Fish Peptide, Marine Products, Protamine

Applications

Functional Foods, Utilization of Marine Bio-resources, Materials of Pharmaceutical Compounds

Research Topics

① Influence of Superchilling (Hyo-On) Treatment on Food Components
② Health Promoting Effect of Novel Component Derive from Seafood

Key Words

Superchilling (Hyo-On), Food Preservation, Aging, Seafood, Fish Protein, Marine Phospholipid

Applications

Food Preservation Technology, Novel Aging Technology, Functional Food and Component

Research Topics

① Explorative study of bioactive compounds
② Synthesis of functional molecules
③ Pharmaceutical engineering

Key Words

Drug Discovery, Natural Products, Molecular Target Drugs, Gene Delivery, Polyphenol, Histone Deacetylase Inhibitor

Applications

Pharmaceuticals, Cosmetics, Dietary Supplements

Research Topics

① Drug discovery of bioactive compounds
② Discovery of natural products
③ Construction of chemical library
④ Identification of molecular mechanism of bioactive compounds

Key Words

Medicinal Chemistry, Protein-Protein Interaction, Epigenetics, Chemical Library, Natural Products, Neurodegenerative disease, Anticancer Drug, Drug Delivery to Brain

Applications

Pharmaceuticals, Drug Discovery

Research Topics

① Development of a drug to reduce jet lag
② Investigation of the regulators underlying the circadian rhythm
③ Elucidation of the molecular mechanisms of the clock genes

Key Words

Circadian rhythm, Suprachiasmatic nucleus, Clock gene

Applications

Health science, Pharmaceutical intervention, Bioreporter, Biosensor

Research Topics

① Cell plate formation in higher plant cells
② The role of microtubule associated proteins in cell division and cell elongation

Key Words

Plant Cytokinesis, Phragmoplast, Cell Plate, Microtubules, Actin Filaments, Cytoskeleton

Applications

Breeding of Plants

Research Topics

① Genetic Engineering of Fish

Key Words

Myogenesis, Development, Medaka, Genetic engineering

Applications

Genetic engineering of aquatic animals, Congenital disease analyses, Drug discovery